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The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal painor sciatica caused by low-back pain with those using both in patients with nonspecific low back pain. We searched Medline, Embase, Embase, CINAHL and Scopus between July 2006 and December 2011, and abstracts were then reviewed for potentially relevant studies. We included all studies comparing the primary efficacy measure of the study group with the matched control group, which we defined as receiving a corticosteroid or NSAID injection at least 2 weeks before a physical examination (the first day of study). We excluded studies of chronic pain where no NSAID was used and those using placebo to measure response between 2 treatment periods. Studies comparing the treatment of pain treated with NSAIDs versus corticosteroids were excluded because patients taking corticosteroids typically reported less pain than NSAID users and/or less pain than patients taking non-steroidal anti-inflammatory drugs. Furthermore, studies comparing the effectiveness of corticosteroids versus NSAIDs were not included because corticosteroid injection is an important part of the maintenance therapy and most people are given a short course (typically 2 weeks) of corticosteroids for their low-back pain or Sciatica. We identified 13 eligible studies: the remaining 5 trials (including trials comparing 1 injection vs 1 placebo or 1 NSAID versus 1 comparator), combined, had been published till December 2011. Of them, 13 trials were of adults, with 9 taking NSAIDs versus 16 NSAID vs 1 corticosteroid infusion, 7 in a single intervention (3 in the corticosteroid injection group and 1 in the NSAID group) and 4 in 2 groups (both NSAIDs and corticosteroids). The mean (SD) age of the patients in all studies, all trials of adults and 2 trials comparing NSAIDs vs corticosteroids (6 in the corticosteroid injection group vs 6 placebo, 1 in the placebo group) ranged from 30-71 years. Six studies compared NSAID vs corticosteroidal injections with 10 trials comparing only the latter group and 2 comparing only in the same interventions (2 studies of adults and 1 study in children and adolescents). The meta-analyses included only studies from the US while the other studies were published in Europe, Asia, Australia, South America, Sub-Saharan Africa, India and the Middle East. Although most studies comparing conventional high-dose corticosteroids with non-drug low back pain did report benefit for the pain level in the corticosteroid injections group, Similar articles:

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Do legal anabolic steroids work, can you buy steroids in tenerife
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